The RRRC has developed a number of diagnostic tests and techniques for utilization in genetic testing for rats. These tests include methods for the detection and identification of chromosomal integration sites and microsatellite markers panels for genetic monitoring of common rat strains.
A restriction enzyme-PCR-based technique to determine transgene insertion sites. Bryda EC, Bauer BA. Methods in Molecular Biology 2010; 597:287-99.
Multiplex microsatellite marker panels for genetic monitoring of common rat strains. Bryda EC, Riley LK. Journal of the American Association for Laboratory Animal Science 2008; 47(3):37-41.
Method for detection and identification of multiple chromosomal integration sites in transgenic animals created with lentivirus. Bryda EC, Pearson M, Agca Y, Bauer BA. Biotechniques 2006; 41(6): 715-9.
05.21.2026
Weather and Shipping
The welfare of the animals is of utmost importance and as we head into the summer months, inclement weather and excessive heat will delay/prevent shipments of live animals. Be aware that hot temperatures between June and mid-September may negatively impact the ability of couriers to safely ship animals so please plan your live animal orders accordingly.
05.21.2026
Provide Your Input on NIH's Proposed Strategic Plan by May 26, 2026.
The NIH is currently seeking input for its next strategic plan, and a major focus of this framework involves the future of animal research. Because these high-level policies directly impact the future of the RRRC and your work, it’s crucial that the scientific community participates. The NIH has provided a short feedback form that only takes a few minutes to complete. Please consider submitting your input. URL: https://grants.nih.gov/
07.30.2025
Animal Models and New Approach Methodologies (NAMs)
NAMs are lab (e.g., organoids and iPSCs) or computer-based methods intended to expand our tools for modeling human biology and disease. While this field is rapidly evolving, the need for animal models remains, especially for situations where a complex biological system is necessary. In addition, animal models serve as vital in vivo controls for the validation and verification of emerging NAMs.