for assistance call: 1-888-673-3444
 
Microbiota Characterization Now Offered
 July 07, 2014
The RRRC now offers a full line of NGS-related services including fecal DNA extraction, 16S rDNA gene sequencing, and informatics analysis to researchers using rat models.  For more information, please see here or contact www.rrrc.us.
Need a New Rat Model?
 March 21, 2017
Need a new rat model?  The RRRC in conjunction with the MU Animal Modeling Core (AMC) can assist with the generation of transgenic rats, create knock-out and knock-in rats using CRISPR/Cas9 technology and genetically manipulate rat embryonic stem cells to make chimeric animals.  Contact us to discuss your rat model needs and how we can help.
Genetics
The RRRC has developed a number of diagnostic tests and techniques for utilization in genetic testing for rats.  These tests include methods for the detection and identification of chromosomal integration sites and microsatellite markers panels for genetic monitoring of common rat strains. 

  1. A restriction enzyme-PCR-based technique to determine transgene insertion sites. Bryda EC, Bauer BA. Methods in Molecular Biology 2010; 597:287-99.

  2. Multiplex microsatellite marker panels for genetic monitoring of common rat strains. Bryda EC, Riley LK. Journal of the American Association for Laboratory Animal Science 2008; 47(3):37-41.

  3. Method for detection and identification of multiple chromosomal integration sites in transgenic animals created with lentivirus.   Bryda EC, Pearson M, Agca Y, Bauer BA.  Biotechniques 2006; 41(6): 715-9.